An herb used in traditional Chinese medicine to treat certain medical problems. Association rule mining and network analysis identified Hedyotis diffusa plus Scutellaria barbata as the most common duplex medicinal (10.9%) used for the core treatment of breast cancer. Used as a medicinal herb O. diffusa flower grows solitary or in pairs in axillary with very short or no peduncle. Further prospective clinical trials are warranted. However, its pharmacological mechanisms have not been fully established and there is a lack of modern scientific verification. Hedyotis diffusa or Oldenlandia diffusa (spreading hedyotis) is one of the most commonly used anticancer herbs. Jia-Wei-Xiao-Yao-San (19.6%) and Hedyotis diffusa (41.9%) were the most commonly prescribed herbal formula (HF) and single herb (SH), respectively. Names of Hedyotis Auricularia in various languages of the world are also given. Hedyotis diffusa Willd. Total flavonoids of Hedyotis diffusa Willd (TFHDW) are active compounds derived from Hedyotis diffusa Willd, which has been long used in Chinese traditional medicine for the treatment of various inflammatory diseases, including ulcerative colitis and bronchitis; however, the precise mechanisms underlying the effects of TFHDW are largely unknown. How Hedyotis Auricularia is effective for various diseases is listed in repertory format. Oldenlandia diffusa, an herb prevalent in East Asia and Southern China, is used in traditional Chinese medicine to clear “heat” and to eliminate “toxins”. In our study, an equal weight combination of Scutellaria barbata and Hedyotis diffusa (SH, specific details in methods and materials) is a classic herb pair used for detoxification and is used frequently in the treatment of cancer and many other diseases. Oldenlandia brachypoda G.Don. Up to now, 171 compounds have been reported from H. diffusa, including 32 iridoids, 26 flavonoids, 24 anthraquinones, 26 phenolics and their derivatives, 50 volatile oils and 13 miscellaneous compounds. In this study, total flavonoids and total triterpenoid acid were extracted with ethyl acetate from Hedyotis diffusa Willd, and hepatoprotective activities of them and five compounds from total flavonoids against H 2 O 2 induced hepatocyte damage on HL‐02 cells were determined. Spreading Hedyotis (Hedyotis diffusa or Oldenlandia diffusa) Known in China as ‘snake needle grass’ or ‘white flower snake-tongue grass’, Hedyotis diffusa or Oldenlandia diffusa (spreading hedyotis) has been used as an anticancer herb for several thousand years and is one of the most renowned herbs prescribed for cancer treatment in Chinese traditional medicine. Masam. Case Reports in Oncological Medicine 2017, 2017, 1-6. It has been used to boost the immune system and may have anticancer effects. Salasik-lupa, Hedyotis verticillata, SHRUBBY FALSE BUTTONWEED - Philippine Herbal Medicine - An illustrated compilation of Philippine medicinal plants by Dr Godofredo Umali Stuart of Philippine medicinal plants with botanical information, chemical properties, folkloric uses … Hedyotis diffusa is a Chinese herbal medicine widely used in combination with other herbal medicines such as Scutellaria barbata to treat various types of cancer. It is sometimes combined with other herbs to make hot drinks like Lohoguo of Guongsei or Luohanguo Pearl and Sheshecao Beverage. Pei-Yuu Yang, Chen-Jei Tai. English dictionary of cancer terms . Hedyotis diffusa. List of various diseases cured by Hedyotis Auricularia. It is a relatively practical and common Chinese herbal medicine, which first appeared in (List of traditional Chinese medicine resources in Guangxi) in 1,959 AD. Dysfunctional metabolisms are contributed to LPS/GALN-induced hepatitis. Hedyotis (starviolet) is a genus of flowering plants in the family Rubiaceae.Many species of this genus such as Hedyotis biflora, H. corymbosa and H. diffusa are well known medicinal plants.Hedyotis is native to tropical and subtropical Asia and to islands of the northwest Pacific. Study suggests Chinese herbal therapy might be associated with reduced mortality among patients with pancreatic cancer. Hedyotis extensa R.Br. Hedyotis radicans Bartl. Oldenlandia corymbosa uniflora (Benth.) ex Wight & Arn. Hedyotis diffusa Plus Scutellaria barbata Are the Core Treatment of CHM for Breast Cancer. Interpretation Translation  Hedyotis diffusa. It is used in combination with other herbs for the treatment of hepatitis, snake bites , and tumors of the liver, lung, stomach , and rectum . 3. Shuijianbi a day. This plant belongs to the botanical coffee family (Rubiaceae). Although recently we reported that EEHDW promotes cancer cell apoptosis via activation of the mitochondrial-dependent pathway, the precise mechanism of its tumoricidalactivity still remains to be clarified. Parties to use Hedyotis diffusa 20g 12g capillaris, Money Grass 20g, Chai Hu 12g, turmeric 15g, Radix 15g, the Cyperus 15g, the gardenia 12g, Salvia 15g, white peony root 15g, licorice 5g. Hedyotis diffusa Willd. It derived from China, where the Danish botanist Henrik Bernard Oldenland discovered it and gave his name to it. Journal of Ethnopharmacology 2017, 196, 253-260. Hedyotis diffusa. Chemistry: Caffeine and fumeric acid. The breast tumor-induced osteolysis in mice was restored by herbal formula treatment, in which the bone volume in treated mice tibia was comparable … Bai Hua She She Cao is also known as Snake Needle Grass, Spreading Hedyotis, Oldenlandia Diffusa, or Hedyotis Diffusa, which is an annual herb belonging to the family Rubiaceae. Its clinical use has a history more than several thousand years. Hedyotis diffusa (Chinese: 白花蛇舌草; pinyin: báihuā shéshécǎo; lit. Hedyotis ramosissima Kurz. It comprises about 115 species. ex Wall. Bai-hua-she-she-cao (Herba oldenlandia: Hedyotis diffusa Spreng) and Xiang-sha-liu-jun-zi-tang (Costus and Chinese Amomum combination) were the most frequently used single herb and Chinese herbal formula. However, the molecular mechanism of the anti-cancer activity of Hedyotis Diffusa Willd remains unclear. Hedyotis diffusa Willd (Oldenlandia diffusa, Rubiaceae) is an ancient Chinese herbal which can be found in Asian countries including China; its aqueous extract (boiled in water) is employed to treat many kinds of diseases . We use the cytokines expression, levels of serum alanine transaminase and aspartate transaminase, survival and histological analysis to measure the effect of decoction of HD on acute severe hepatitis of mouse … However, whether Hedyotis diffusa (HD) employs metabolic strategies against hepatitis is unknown. A study reported that two-thirds TCM practitioners used S. barbata and H. diffusa to treat cancer (Meng et al., 2013). Oldenlandia diffusa, Hedyotis diffusa. Medicinal Use: Useful in gastric irritability, nervous depression, liver complaints and fever. General information about Hedyotis diffusa (HYODI) Himalayas, India, Sri Lanka, Bangladesh, China (including Taiwan), Japan, Korea, Indochina, Malesia. Our results showed that the breast tumor weight as well as lung and liver metastasis in mice could be reduced after herbal formula treatment for 4 weeks. were eventually selected to form an innovative herbal formula. Total coumarins of Hedyotis diffusa induces apoptosis of myelodysplastic syndrome SKM-1 cells by activation of caspases and inhibition of PI3K/Akt pathway proteins. Hedyotis diffusa from which the Chinese herb Bai Hua She She Cao is obtained is also known as white flower snake-tongue grass or snake needle grass and can be found in China, Japan, India, Thailand and Nepal.. Air-dried plant: alkaloids and biflorone. (Rubiaceae) is an important folk herb used to prevent and cure hepatitis and liver cancer in Taiwan. DOI: 10.1016/j.jep.2016.12.012. This study was undertaken to assess the therapeutic effects and reveal detailed mechanisms of H.diffusa for oncotherapy. Common Name: No Image. Oldenlandia pauciflora Roxb. Hedyotis diffusa Willd has been used as a major component in several Chinese medicine formulas for the clinical treatment of colorectal cancer (CRC). Hedyotis polygonoides Wall. Hedyotis Diffusa Willd has been used as a major component in several Chinese medicine formulations for the clinical treatment of colorectal cancer. ex DC. However, the precise mechanism of its anti-tumor activity remains largely unclear. For differentiation of H. diffusa from counterfeits, macroscopic and microscopic characters of H. diffusa, H. corymbosa and H. tenelliflora were examined in this study. Hedyotis diffusa Willd (H. diffusa) is a well-known Chinese medicine with a variety of activities, especially its anti-cancer effect in the clinic. Hedyotis Diffusa Willd (EEHDW) has long been used as an important component in several TCM formulas to treat various types of cancer. Its second and more common scientific name is Oldenlandia diffusa. Molecules 2018 , 23 (7) , 1525. Hedyotis diffusa, also known as white flower snake-tongue grass or snake needle grass, is an important herb in traditional Chinese medicine. Hedyotis diffusa is an herb used for anti-cancer, anti-oxidant, anti-inflammatory, and anti-fibroblast treatment in the clinical practice of Traditional Chinese Medicine. Clinical Summary. Oldenlandia herbacea uniflora Benth. The control group was MNK-45 cells without added hedyotis diffusa; the 3 groups of experimental groups were treated with hedyotis diffusa at final concentrations of 20 , 30, 40 μg / ml respectively; each group was incubated for 48 h in a 5% carbon dioxide incubator, and the morphological changes of the cells were observed under a laser confocal microscope. Hedyotis diffusa, a traditional Chinese herbal medicine, is widely used for oncotherapy and shows a positive effect in the clinical treatment.But its mechanism of anticancer activities is complicated and unclear. Hedyotis diffusa Willd Inhibits Colorectal Cancer Growth in Vivo via Inhibition of STAT3 Signaling Pathway Q. Cai , J. Lin , +8 authors Jun Peng International journal of molecular sciences Background: The Scutellaria barbata – Hedyotis diffusa herb pair has appeared in classical prescriptions and has usually been used for the treatment of cancer and inflammatory conditions. The key finding of this study is that Hedyotis diffusa plus Scutellaria barbata was the core CHM treatment for breast cancer. Chinese Medicine Treatment for Afatinib-Induced Paronychia. Part used: Whole plant : Medicinal Properties: Alterative, febrifuge and anthelmintic. :: Results. The type species for the genus is Hedyotis fruticosa. Discovery of the Potential Biomarkers for Discrimination between Hedyotis diffusa and Hedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis. Ethnobotanical Uses: Food (Herb and Spice) Medicinal ( Oldenlandia diffusa has been used by the Chinese for medicinal purpose for the treatment of colorectal cancer. Uses, Benefits, Cures, Side Effects, Nutrients in Hedyotis Auricularia. 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